Hippocampal Sclerosis in LGI1 and CSPR2 Positive Limbic Encephalopathy: Case Report
نویسندگان
چکیده
10.4172/Neuropsychiatry.1000256 © 2017 pISSN 1758-2008 eISSN 1758-2016 Neuropsychiatry (London) (2017) 7(5), 615–619 615 1Postgraduate Resident of Neurology, Department of Neurology, West China Hospital, Sichuan University, 610041 Chengdu, P.R. China 2Head of Neurology, Department of Neurology, West China Hospital, Sichuan University, 610041 Chengdu, P.R. China 3 Neurologist, Department of Neurology, West China Hospital, Sichuan University, 610041 Chengdu, P.R. China †Author for correspondence: JinMei Li, Assistant Professor, Department of Neurology, West China Hospital, Sichuan University, 610041 Chengdu, P.R. China. Tel: +86-18628280713, email: [email protected] Hippocampal Sclerosis in LGI1 and CSPR2 Positive Limbic Encephalopathy: Case Report
منابع مشابه
Voltage-gated potassium channel/LGI1 antibody-associated encephalopathy may cause brief psychotic disorder.
To the Editor: Voltage-gated potassium channel (VGKC) antibody–associated encephalopathy has been identified as a potentially immunotherapy-responsive form of limbic encephalitis.1 A recent study showed that the target antigen in this condition is in fact LGI1, a secreted neural protein that functions as a ligand for 2 epilepsy-related proteins, ADAM22 and ADAM23.2 Limbic encephalitis is typica...
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BACKGROUND Voltage-gated potassium channel antibodies (VGKC Ab) are associated with limbic encephalitis and neuromyotonia in adults. There have been no systematic investigations in children to date. METHODS We looked for antibodies that are associated with CNS syndromes in adults including antibodies to VGKCs, NMDARs, glutamic acid decarboxylase (GAD), and glycine receptor (GlyR) in the store...
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BACKGROUND Voltage-gated potassium channels are thought to be the target of antibodies associated with limbic encephalitis. However, antibody testing using cells expressing voltage-gated potassium channels is negative; hence, we aimed to identify the real autoantigen associated with limbic encephalitis. METHODS We analysed sera and CSF of 57 patients with limbic encephalitis and antibodies at...
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Anti-leucine-rich glioma inactivated-1 (LGI1) limbic encephalitis (LE) is a rare neurological disorder that has a subacute course of progressive encephalopathy and fasciobrachial dystonic seizures. We report a patient with anti-LGI1 LE that presented with atypical manifestations that complicated the diagnosis. A 62-year-old woman presented with a chronic course of memory disturbance and a subse...
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